Synthesis of a new enantiomerically pure constrained homoserine

Article abstract of DOI:10.1016/0957-4166(96)00067-5

The use of the Diels-Alder reaction between 1,3-butadiene and chiral 2-acetamidoacrylates as the key step followed by stereocontrolled transformations allows the synthesis of (1S,3R)-1-amino-3-hydroxycyclohexanecarboxylic acid, a new type of constrained h