Synthesis and serotonergic activity of arylpiperazide derivatives of serotonin: Potent agonists for 5-HT(1D) receptors

DOI: 10.1021/jm00018a020

Source and publish data:

Journal of Medicinal Chemistry p. 3602 - 3607 (1995)

Update date:2022-07-29

Topics:

Authors:

Perez Perez

Fourrier

Sigogneau

Pauwels Pauwels

Palmier Palmier

John John

Valentin

Halazy Halazy

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Article abstract of DOI:10.1021/jm00018a020

A series of new arylpiperazide derivatives of serotonin has been prepared and evaluated as 5-HT(1D) receptor agonists. Binding experiments at cloned human 5-HT(1Dα), 5-HT(1Dβ), and 5-HT(1A) receptors show that all the compounds are very potent and selecti

Full text of DOI:10.1021/jm00018a020

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