Synthetic study on hapalosin, a cyclic depsipeptide possessing multidrug resistance reversing activities

DOI: 10.1016/0040-4039(96)00592-8

Source and publish data:

Tetrahedron Letters p. 3467 - 3470 (1996)

Update date:2022-08-04

Topics: Multidrug resistance Cyclic Experimental Synthetic study Depsipeptide

Authors:

Ohmori, Ken

Okuno, Toshiaki

Nishiyama, Shigeru

Yamamura, Shosuke

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Article abstract of DOI:10.1016/0040-4039(96)00592-8

Hapalosin possessing a multidrug resistance reversing activity, has been synthesized from the corresponding hydroxy acids and γ-amino acids. The stereochemistry of the natural product and related derivatives is discussed.

Full text of DOI:10.1016/0040-4039(96)00592-8

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