Efficient construction of 6-azasteroids: Dual inhibitors of steroidal 5α-reductase

DOI: 10.1016/S0960-894X(98)00611-8

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 3291 - 3294 (1998)

Update date:2022-08-04

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Authors:

Sharp, Matthew J.

Fang, Francis G.

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Article abstract of DOI:10.1016/S0960-894X(98)00611-8

A new route to 17β-substituted-6-azaandrost-4-en-3-ones, potent dual inhibitors of type 1 and 2 steroidal 5 α-reductase, is described.

Full text of DOI:10.1016/S0960-894X(98)00611-8

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Product name:17β-carbomethoxy-6-nitrilo-5-oxo-5,6-secoandrost-3-ene

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