Tetrahedron Letters p. 3421 - 3434 (1996)
Update date:2022-08-03
Topics:
Cao
Roy
GM3-trisaccharide [Neu5Acα-)2 → 3)-Galβ-(1 → 4)-Glcβ-(1 → OR] was synthesized using our 'active-latent' thioglycosylation strategy. The trisaccharide was prepared with a p-acrylamidophenyl aglycon for copolymerization with acrylamide. The resulting water-soluble sialyl α-(2 → 3)-lactoside copolyacrylamide with different carbohydrate incorporation was shown to possess antigenic properties.
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