Tetrahedron Letters p. 3643 - 3646 (1996)
Update date:2022-08-03
Topics:
Jones, Graham B.
Huber, Robert S.
Mathews, Jude E.
Li, Aiwen
Enediyne estrogen conjugates have been prepared from readily available precursors. Enediyne 12 causes significant DNA strand scission at 10-3 M, and has demonstrated cytotoxicity against the ER rich MCF-7 human breast cancer cell line.
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