Synthesis and characterization of a carbene-generating biotinylated lactosylceramide analog as a novel chromogenic photoprobe for GM3 synthase

DOI: 10.1248/cpb.44.1111

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Chemical and Pharmaceutical Bulletin p. 1111 - 1114 (1996)

Update date:2022-08-03

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Authors:

Hatanaka, Yasumaru

Hashimoto, Makoto

Jwa Hidari, Kazuya I.-P.

Sanai, Yutaka

Tezuka, Yasuhiro

Nagai, Yoshitaka

Kanaoka, Yuichi

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Article abstract of DOI:10.1248/cpb.44.1111

A new biotinylated lactose derivative bearing a nitro-substituted chromogenic diazirine was synthesized. The biotinyl group within the structure enabled the performance of a convenient assay of GM₃ synthase based on avidin-biotin technology, an

Full text of DOI:10.1248/cpb.44.1111

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