Synthesis of diphenyl phosphonate analogues of tyrosine and tryptophan and derived peptides as chymotrypsin inhibitors

DOI: 10.1039/cc9960001155

Source and publish data:

Chemical Communications p. 1155 - 1156 (1996)

Update date:2022-08-03

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Authors:

Bergin, Carol

Hamilton, Robert

Walker, Brian

Walker, Brian J.

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Article abstract of DOI:10.1039/cc9960001155

The synthesis of α-aminophosphonate analogues of tyrosine and tryptophan, e.g. 4 and 5 respectively, and their incorporation into proline-containing dipeptides is reported; of the sequences synthesised, the dipeptide Z-Pro-Trp(P)(OPh)₂ is the o

Full text of DOI:10.1039/cc9960001155

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