Bryophyte constituents; 7: New synthesis of (+)-rosmarinic acid and related compounds

Article abstract of DOI:10.1055/s-1996-4289

Efficient and expeditious syntheses are described for rosmarinic acid (1) and its derivatives 2-4, making extensive use of allyl protective groups for both carboxylic acids and phenolic building blocks. (+)(R)-Rosmarinic acid was obtained by a chemoenzymatic resolution of its phenyl lactic acid precursors.