Tetrahedron Letters p. 4363 - 4364 (1996)
Update date:2022-08-03
Topics:
Bach, Thorsten
Lange, Christian
2-Aryloxetanes 3 are cleaved at the C-2 position upon treatment with lithium aluminium hydride to deliver the triols 4 in good yields (61-85 %). The regioselective ring opening at the more hindered position is facilitated by a hydoxyl group attached to the arene.
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