Synthesis and antitumor activity of novel distamycin derivatives

DOI: 10.1016/0960-894X(96)00204-1

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 1241 - 1246 (1996)

Update date:2022-08-03

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Authors:

Baraldi, Pier Giovanni

Beria, Italo

Cacciari, Barbara

Cozzi, Paolo

Franzetti, Cristina

Mongelli, Nicola

Romagnoli, Romeo

Spalluto, Giampiero

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Article abstract of DOI:10.1016/0960-894X(96)00204-1

Several distamycin derivatives were synthesized from deformyl distamycin by coupling with different azole carboxylic acids bearing an alkylating moiety. Some of them showed good activities in vitro and in vivo against L 1210 murine leukemia.

Full text of DOI:10.1016/0960-894X(96)00204-1

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