Bioorganic and Medicinal Chemistry Letters p. 1399 - 1402 (1996)
Update date:2022-08-04
Topics:
Roy, Rene
Park, William K. C.
Srivastava, Om P.
Foxall, Carrol
Stepwise large scale synthesis of 3'-sulfo-Lewis(X)-Glc mimetic of the lead anti-inflammatory agent sialyl Lewis(X) in a form suitable for copolymerization with acrylamide has been achieved. The resulting water- soluble copolyacrylamide showed inhibition of binding of both L- and E- selectins in the μMolar range.
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