Bioorganic and medicinal chemistry letters p. 2365 - 2370 (1999)
Update date:2022-09-26
Topics:
Peet
Kim
Marquart
Angelastro
Nieduzak
White
Friedrich
Flynn
Webster
Vaz
Linnik
Koehl
Mehdi
Bey
Emary
Hwang
The synthesis of [1-[(5-hydroxy-4-(phenylmethyl)-3-oxazolidinyl)carbonyl]-2-ethylpropy lcarbamic acid phenylmethyl ester (2; MDL 104,903), a potent inhibitor of calpain, is described. Synthesis of related compounds, which offer insights into the mechanism of action for 2, are also described, as is an O-acetyl prodrug derivative of 2.
View MoreContact:86-551-63540590
Address:No 1388 Furong Rd., Hefei, Anhui, China
Neworld Chemical Co., Ltd Shanghai(expird)
Contact:+86-21-62202658
Address:11F, Blvd 2, No. 1969 PuXing Rd, Shanghai
Shanghai Xinda Pharmaceuticals Co., Ltd.
Contact:86-21-33692333-8008
Address:999 Linxian Road, Jinshan Industrial Park, Shanghai, China
PINGYUAN SIHUAN PHARMACEUTICAL CO., LTD
Contact:+86-531-55696072
Address:#2766,yinxiu Road, Economic Development Zone, Pingyuan Country, Shandong Province, China.
Zhejiang Kangfeng Chemical Co.,LTD.
Contact:+86-579-86709687
Address:Xueshizhai Industrial Zone, Weishan Town,Dongyang City, Zhejiang Province ,China
Doi:10.1021/ja01468a040
(1961)Doi:10.1021/ja962086v
(1996)Doi:10.1016/S0022-328X(97)00075-2
(1997)Doi:10.1007/BF00474882
()Doi:10.1021/acs.orglett.1c01477
(2021)Doi:10.1016/S0040-4020(97)00997-6
(1997)
