Studies on quinazolines. 6. Asymmetric synthesis of (S)-(+)- and (R)-(-)-3-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-5-methylthio-2,3- dihydroimidazo[1,2-c]quinazolines

DOI: 10.1016/0957-4166(96)00198-X

Source and publish data:

Tetrahedron Asymmetry p. 1641 - 1648 (1996)

Update date:2022-07-29

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Authors:

Gutcait, Alexander

Wang, Kuang-Chao

Liu, Hsiu-Wen

Chern, Ji-Wang

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Article abstract of DOI:10.1016/0957-4166(96)00198-X

The titled compounds have been synthesized in five steps from commercially available (R)-(+) and (S)-(-)-glycidol. The overall yield was about 29% with ee>98.5%. Copyright

Full text of DOI:10.1016/0957-4166(96)00198-X

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