Cyclic carbopalladation of alkynes terminated by carbonylative amidation

Article abstract of DOI:10.1016/0040-4020(96)00640-0

Termination of cyclic carbopalladation of alkynes via carbonylative lactamization can be achieved more satisfactorily with alkenyl or aryl halides containing an ω-carboxamido or ω-sulfonamido group than with those containing an ω-amino group. The method appears to be generally satisfactory for the preparation of fused cyclic systems consisting of six-membered rings, while the other cases require further development.