Bioorganic and Medicinal Chemistry Letters p. 3571 - 3576 (1998)
Update date:2022-07-30
Topics:
Masaguer, Christian F.
Formoso, Emilio
Ravina, Enrique
Tristan, Helena
Loza, M. Isabel
Rivas, Emilia
Fontenla, Jose Angel
We describe a practical and efficient route for synthesis of 2- aminomethyl-1,2,3,9-tetrahydro-4H-carbazol-4-ones using an effective Fisher indole methodology. The most active compounds, 4b (QF 2003B) and 4c (QF 2004B), with pKi (5-HT(2A)/D2) r
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Doi:10.1021/jo9805192
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