Butyrophenone analogues in the carbazole series: Synthesis and determination of affinities at D2 and 5-HT(2A) receptors

DOI: 10.1016/S0960-894X(98)00639-8

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 3571 - 3576 (1998)

Update date:2022-07-30

Topics:

Authors:

Masaguer, Christian F.

Formoso, Emilio

Ravina, Enrique

Tristan, Helena

Loza, M. Isabel

Rivas, Emilia

Fontenla, Jose Angel

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0960-894X(98)00639-8

We describe a practical and efficient route for synthesis of 2- aminomethyl-1,2,3,9-tetrahydro-4H-carbazol-4-ones using an effective Fisher indole methodology. The most active compounds, 4b (QF 2003B) and 4c (QF 2004B), with pKi (5-HT(2A)/D₂) r

Full text of DOI:10.1016/S0960-894X(98)00639-8

Products guided by the article

Product name:N,N-diethyl-3,5-dimethoxy-1,4-dihydrobenzylamine

Cas No:181047-37-0

R&D Labs maybe for 181047-37-0

Changzhou Sunsheng Chem Co., Ltd

Contact:+1-(989)-854-0648

Address:No. 28 Yinshan Rd., Xixiashu Industrial Park
Jiangsu Cale New Material Co.ltd

Contact:+86-515-88334667/88203550

Address:Zhongshan 3rd Road, Coastal Chemical Industry Park, Yancheng, Jiangsu, China
SPRING CHEMICAL INDUSTRY CO.,LTD

Contact:86-187-66672125

Address:linchi industry park.zouping
SHANXI JINJIN CHEMICAL INDUSTRIAL CO.,LTD

website:http://www.jinjingroup.com

Contact:86-574-13989382828

Address:Economic And Technological Development Zone,Hejin?City,Shanxi Province?,China
UNION PHARMPRO CO.,LTD

Contact:18710867521(wechat)

Address:Rm10516,Galaxy Tech Building #2,No.25 Tangyan Rd,Hi-Tech Zone,Xi'an, China

Relevant to this article

Efficient total synthesis of (-)-ilimaquinone

Doi:10.1021/jo9805192
(1998)
Novel functionalised Troger's bases: Synthesis of a new class of Troger's base analogues containing dicarboxyl functionality

Doi:10.1016/0040-4039(96)01227-0
(1996)
Synthesis and preliminary evaluation of curcumin analogues as cytotoxic agents

Doi:10.1016/j.bmcl.2010.12.020
(2011)
Convenient synthesis of hetero decalins

Doi:10.1080/00397919608003761
(1996)
α-Zinc O-vinyl carbamates as anionic Friedel-Crafts equivalents. Cross coupling reactions with aryl and heteroaryl halides and triflates

Doi:10.1016/0040-4039(96)01314-7
(1996)
Syntheses of 4-(2-hydroperoxy-2,2-diarylethyl)-3,5-dimethylpyrazoles, 4-(2-hydroxy-2,2-diarylethyl)-3,5-dimethylpyrazoles and the related compounds

Doi:10.1002/jhet.5570330448
(1996)

Article Doi