A new method to modify the C-4 position of 10-deacetylbaccatin III

DOI: 10.1248/cpb.45.2093

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 2093 - 2095 (1997)

Update date:2022-07-29

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Authors:

Uoto, Kouichi

Takenoshita, Haruhiro

Ishiyama, Takashi

Terasawa, Hirofumi

Soga, Tsunehiko

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Article abstract of DOI:10.1248/cpb.45.2093

We have developed a new method to modify the C-4 position of 10- deacetylbaccatin III (5) using the C-4 acetoxy anion of the 13-keto derivative (7) and various alkyl halides. The method developed herein should be very useful for the preparation of C-4 mod

Full text of DOI:10.1248/cpb.45.2093

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