Synthesis of [3.3.0] bicyclic isoxazolidinyl nucleosides

DOI: 10.1016/S0960-894X(96)00262-4

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 1475 - 1478 (1996)

Update date:2022-08-03

Topics:

Authors:

Xiang, Yuejun

Schinazi, Raymond F.

Zhao, Kang

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0960-894X(96)00262-4

The isoxazolidine derivative 6, prepared from an intermolecular 1,3- dipolar cycloaddition of the (5S)-unsaturated lactone 5 and N-methylnitrone, was effectively used for the synthesis of [3.3.0] bicyclic isoxazolidinyl cytidine 4a and thymidine 4b.

Full text of DOI:10.1016/S0960-894X(96)00262-4

Products guided by the article

Product name:N-{1-[(3aR,4R,6R,6aS)-6-(tert-Butyl-diphenyl-silanyloxymethyl)-2-methyl-hexahydro-furo[3,4-d]isoxazol-4-yl]-2-oxo-1,2-dihydro-pyrimidin-4-yl}-benzamide

Cas No:181632-01-9

R&D Labs maybe for 181632-01-9

NANCHANG QINZHI SCI&TEC.CO.,LTD(expird)

Contact:+86-13687004106

Address:Hero South Road,Hero Zone,Nanchang,Jiangxi,China
SHANDONG ZHANHUA YONGHAO PHARMACEUTICAL TECH.CO.,LTD

Contact:+86-576-88685096

Address:GENGJU VILLAGE NORTH ONE KILOMETER,ZHANHUA DISTRICT,BINZHOU CITY,SHANDONG PROVINCE,CHINA.
Changchun BC＆HC Pharmaceutical Technology Co.,Ltd

Contact:+86-0431-80871588, +86-0431-80871788

Address:NO.668#Chuangxin road, Gaoxin District, Changchun ,Jilin
Wuhan Hanye Chemical New Material Co.,Ltd

Contact:+86-27-85308141

Address:LiuDian, Panlongcheng Economic Development Zone, HuangPi district, Wuhan, Hubei 430311 P.R.China
Changsha Goomoo Chemical Technology Co.Ltd

Contact:+86-731-82197655

Address:No.649,Chezhan Rd.(N),Changsha,Hunan,China

Relevant to this article

Design and synthesis of piperidinyl piperidine analogues as potent and selective M₂ muscarinic receptor antagonists

Doi:10.1016/S0960-894X(00)00457-1
(2000)
Doi:10.1021/ja01283a023
(1937)
Complexation of (N,N-diethylthiocarbamoylmethyl)diphenylphosphine sulfide with silver nitrate. The structure of the [Ag{Ph₂P(S)CH₂C(S)NEt₂}₂]NO ₃ complex

Doi:10.1007/BF02495219
(1997)
Doi:10.1039/j29700000492
(1970)
Synthesis of optically active β,γ-alkynylglycine derivatives

Doi:10.1016/0040-4020(96)00630-8
(1996)
Asymmetric Acylation of sec-Alcohols with Twisted Amides Possessing Axial Chirality Induced by the Adjacent Asymmetric Center

Doi:10.1021/jo990892p
(1999)

Article Doi