The asymmetric synthesis of allylglycine and other unnatural α-amino acid via zinc-mediated allylation of oximes in aqueous media

Article abstract of DOI:10.1016/0040-4039(96)01118-5

Enantiomerically pure or highly enriched allylglycine and its chain-substituted analogs are easily accessible from the reaction of the sultam derivative of O-benzyl glyoxylic acid oxime with allylic bromides in the presence of powdered zinc in aqueous ammonium chloride.