The nitration of some 1-aryl(or benzyl)pyrroles

Article abstract of DOI:10.1002/jhet.5570330314

Nitration of 1-arylpyrroles 1a-c with acetyl nitrate, and 1-arylpyrroles, 1a-e and 1-(2-ethoxycarbonylbenzyl)pyrrole 4 with trifluoroacetyl nitrate gave the corresponding 2-nitro isomers 2a-e and 5, and 3-nitro isomers 3a-e and 6. 3-Nitropyrroles 3d and 3e were further nitrated with a mixture of nitric and sulfuric acids to give compounds 10, 11 and 12, respectively. Under the same conditions 1-(2-ethoxycarbonylbenzyl)-3-nitropyrrole 6 gave derivative 13.