Bioorganic and Medicinal Chemistry Letters p. 2087 - 2090 (1996)
Update date:2022-08-05
Topics:
Huang, Tien L.
Zhang, Qian
White, Angele T.
Queener, Sherry F.
Bartlett, Marilyn S.
Smith, James W.
Donkor, Isaac O.
A series of novel piperidine-linked aromatic diimidazolines (3-7) have been synthesized as conformationally restricted congeners of the anti-Pneumocystis carinii drug, Pentamidine. These compounds significantly inhibited the growth of Pneumocystis carinii in culture at 1 μg/mL.
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Doi:10.1002/anie.202001419
(2020)Doi:10.1016/S0960-894X(99)00365-0
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(1999)Doi:10.1016/S0022-328X(99)00269-7
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