A versatile mechanism based reaction probe for the direct selection of biocatalysts

DOI: 10.1016/0960-894X(96)00379-4

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 2117 - 2120 (1996)

Update date:2022-07-30

Topics:

Authors:

Lo, Lee-Chiang

Lo, Chih-Hung L.

Janda, Kim D.

Kassel, Daniel B.

Raushel, Frank M.

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Article abstract of DOI:10.1016/0960-894X(96)00379-4

A mechanism based reaction probe was synthesized and shown to modify a bacterial phosphotriesterase; this strategy for generating a probe is general and should allow the isolation of a host of unique catalysts.

Full text of DOI:10.1016/0960-894X(96)00379-4

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