112. Synthesis, conformational properties, and synthetic applications of novel optically pure α,α-disubstituted (R)- and (S)-glycines ('α-chimeras') combining side chains of Asp, Glu, Leu, Phe, Ser, and Val

Article abstract of DOI:10.1002/hlca.19960790508

A series of novel open-chain and cyclic conformationally constrained α,α-disubstituted (R)- and (S)-glycine derivatives ('α-chimeras') combining side chains of Asp, Glu, Leu, Phe, Ser, and Val have been efficiently synthesized by using α-alkylation of rac