Dehydrooligopeptides. XIV. Syntheses of 2-[(Z)-1-amino-1-alken-1-yl]oxazole-4-carboxylic acid and the main common skeleton of thiostrepton peptide antibiotics, A10255G and J

Article abstract of DOI:10.1246/bcsj.69.2309

The practical synthesis of a unique dehydropentapeptide (2), the common main skeleton of thiostrepton macrocyclic peptide antibiotics, A10255G and J, is described. Peptide 2 is constructed from a novel 2-[(Z)-1-amino-1-propen-1-yl]oxazole-4-carboxylic aci