N-type calcium channel blockers from a marine bacterium, Cytophaga sp. SANK 71996

Article abstract of DOI:10.7164/antibiotics.50.457

N-(3-Acyloxyacyl)glycines were isolated as N-type calcium channel blockers from a marine bacterium Cytophaga sp. SANK 71996. The identification and fermentation of the producing strain and structure characterization of N-(3-acyloxyacyl)glycines by spectral analyses and chemical syntheses are described together with their antagonistic activities.