
Bioorganic and Medicinal Chemistry Letters p. 2399 - 2404 (1996)
Update date:2022-08-02
Topics:
Jones Jr.
Elmaleh
Strauss
Fischman
7,10-Bis(2-mercapto-2-methyl)propyl-7,10-diazapalmitic acid (7) was synthesized and evaluated as a new ligand for technetium-99m (99mTc). The title fatty acid analog, an achiral, bis(aminoethanethiol) derivative in which the amines are tertiary, gave a stable complex with 99mTc. The biodistribution of 99mTc-labeled 7 in rats is reported.
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(1996)