Journal of the Chemical Society. Perkin transactions I p. 1467 - 1479 (1996)
Update date:2022-08-02
Topics:
Terfort, Andreas
Brunner, Henri
A series of new, chiral phosphanes is presented, individual members of which were designed to serve as ligands in transition-metal mediated asymmetric Grignard cross coupling reactions. These ligands are characterized by a side chain containing one or two oxygen atoms with the capacity to act as binding sites for the incoming Grignard reagent. A number of structural parameters for the compounds was varied to learn about the reaction mechanism. Most of the ligands were tested in two cross coupling reactions, the formation of 3-phenylbut-1-ene and of 2,2′-dimethyl-1,1′-binaphthyl, respectively. Although both systems gave modest enantiomeric excesses it was not possible to make a comparison of their respective abilities.
View MoreZhangjiagang Golden Reach Fine Chemical Co.,LTD.
Contact:+86-512-6585 6968
Address:Changfu Road， Dongsha Chemical Industry Park, Zhangjiagang City, Jiangsu Province, China
Hebei Kangtai Pharmaceutical Co.,Ltd
Contact:+86-0317-3512963
Address:Wugang Road,Mengcun of Cangzhou City,Hebei Province ,China
Chengdu Green technology Co.,Ltd.
Contact:86-28-82608355
Address:C9 ,Economic Headquarters, Economic Development Zone, Chengdu.
Shanghai Sinofluoro Scientific Co., Ltd
Contact:+86-21-64279360
Address:Room 1006,Building 3,#58 East Xinjian Road, Shanghai ,201100,China,
Contact:86-21 60347964
Address:No.1304, West Meilong Road, Minhang District, Shanghai, China
Doi:10.1080/00397910600640388
(2006)Doi:10.1021/jo961280x
(1996)Doi:10.1021/om960760b
(1997)Doi:10.1016/j.tetasy.2011.08.015
(2011)Doi:10.1021/om960698i
(1996)Doi:10.1016/S0957-4166(99)00568-6
(2000)
