Syntheses of highly constrained β-aryl isohexanoic acid derivatives via asymmetric Michael addition

DOI: 10.1016/0040-4039(96)01795-9

Source and publish data:

Tetrahedron Letters p. 7917 - 7920 (1996)

Update date:2022-08-02

Topics:

Authors:

Liao, Subo

Han, Yinglin

Qiu, Wei

Bruck, Michael

Hruby, Victor J.

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Article abstract of DOI:10.1016/0040-4039(96)01795-9

A series of enantiomerically pure highly sterically hindered β-branched isohexanoic acid derivatives have been synthesized with high diastereoselectivity via asymmetric Michael addition. The X-ray crystal structure of (4S,3'S)-3-[3'-(2,6-dimethylphenyl)is

Full text of DOI:10.1016/0040-4039(96)01795-9

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