Syntheses of highly constrained β-aryl isohexanoic acid derivatives via asymmetric Michael addition

DOI: 10.1016/0040-4039(96)01795-9

Source and publish data:

Tetrahedron Letters p. 7917 - 7920 (1996)

Update date:2022-08-02

Topics:

Authors:

Liao, Subo

Han, Yinglin

Qiu, Wei

Bruck, Michael

Hruby, Victor J.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0040-4039(96)01795-9

A series of enantiomerically pure highly sterically hindered β-branched isohexanoic acid derivatives have been synthesized with high diastereoselectivity via asymmetric Michael addition. The X-ray crystal structure of (4S,3'S)-3-[3'-(2,6-dimethylphenyl)is

Full text of DOI:10.1016/0040-4039(96)01795-9

Products guided by the article

Product name:(3'S,4S)-3-[3'-(4''-methoxyphenyl)-4'-methylpentanoyl]-4-phenyloxazolidin-2-one

Cas No:184784-33-6

R&D Labs maybe for 184784-33-6

Shanghai Korey Pharm Co.,Ltd.(expird)

Contact:021-61840961 021-61840962

Address:No.157,Zhuguang Rd, Qingpu, Shanghai, China
JIANGXI AIFEIMU TECHNOLOGY CO.，LTD

Contact:+86-570-6040289

Address:FINECHEMICAL PARK,ZIBU TOWN,WANNIAN COUNTY,JIANGXI PROV.,CHINA,ZIP
Nanjing Vincero International Trading Co.,Ltd

Contact:8618936897229

Address:NO.68, ZhuShan Road, JiangNing WanDa Plaza, Building E Room 1703
Shenyang NovPharm Technology Co., Ltd.

Contact:.+86-24-24165786

Address:Room 306, Hongjin Mansion, No. 36-1, Wanliutang Rd., Shenhe District, Shenyang, Liaoning, P.R.C.
Suzhou Chiral Pharmaceuticals Co., Ltd.

Contact:86-0512-63197058

Address:Building A, No. 2358, Chang'an Road, Wujiang Science Park

Relevant to this article

A facile, KF/Al₂O₃ mediated method for the preparation of functionalized pyrido[2,3-d]pyrimidin-7(8H)-ones

Doi:10.1016/j.tetlet.2006.02.155
(2006)
2-Substituted aminopyrido[2,3-d]pyrimidin-7(8H)-ones. Structure-activity relationships against selected tyrosine kinases and in vitro and in vivo anticancer activity

Doi:10.1021/jm9802259
(1998)
Asymmetric synthesis of bicyclopropane derivatives

Doi:10.1016/S0040-4020(96)00934-9
(1996)
Differentiation and assigment of the proton NMR signals in the bis-MTPA ester of meso-α,α'-dimethyl-1,4-benzenedimethanol

Doi:10.1016/0957-4166(96)00378-3
(1996)
5α-Androst-16-en-3α-ol β-D-glucuronide, precursor of 5α-androst-16-en-3α-ol in human sweat

Doi:10.1002/cbdv.201300286
(2013)
Optimization of a Dicarboxylic Series for in Vivo Inhibition of Citrate Transport by the Solute Carrier 13 (SLC13) Family

Doi:10.1021/acs.jmedchem.5b01752
(2016)

Article Doi