Asymmetric synthesis of bicyclopropane derivatives

Article abstract of DOI:10.1016/S0040-4020(96)00934-9

Both syn- and anti-bicyclopropane derivatives have been efficiently prepared with good relative and absolute stereocontrol using reagent controlled asymmetric cyclopropanation reactions. Double Simmons-Smith cyclopropanation of 2,4-dien-1-ols stereoselectively gave the corresponding anti-bicyclopropane derivatives.