New strategy for the synthesis of the taxane diterpenes: Formation of the A-ring and introduction of the C-1 hydroxyl group

DOI: 10.1016/00404-0399(50)1084U-

Source and publish data:

Tetrahedron Letters p. 5331 - 5334 (1995)

Update date:2022-08-02

Topics:

Authors:

Magnus, Philip

Booth, John

Magnus, Nicholas

Tarrant, James

Thom, Stephen

Ujjainwalla, Feroze

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Article abstract of DOI:10.1016/00404-0399(50)1084U-

The A-ring of the taxanes is conveniently made from an ester-sulfone condensation, and is compatible with the 1-hydroxyl group, thus completing the synthesis of the ABC-rings.

Full text of DOI:10.1016/00404-0399(50)1084U-

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