New strategy for the synthesis of the taxane diterpenes: Formation of the A-ring and introduction of the C-1 hydroxyl group

DOI: 10.1016/00404-0399(50)1084U-

Source and publish data:

Tetrahedron Letters p. 5331 - 5334 (1995)

Update date:2022-08-02

Topics:

Authors:

Magnus, Philip

Booth, John

Magnus, Nicholas

Tarrant, James

Thom, Stephen

Ujjainwalla, Feroze

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/00404-0399(50)1084U-

The A-ring of the taxanes is conveniently made from an ester-sulfone condensation, and is compatible with the 1-hydroxyl group, thus completing the synthesis of the ABC-rings.

Full text of DOI:10.1016/00404-0399(50)1084U-

Products guided by the article

Product name:(+)-11β-cyano-4α-(tert-butyldimethylsilyl)oxymethyl-3α,10α-oxido-1α-(2'-phenylsulfonylethyl)-8β,12,12-trimethylbicyclo<6.4.0^3,8>dodecan-2-one

Cas No:185013-52-9

R&D Labs maybe for 185013-52-9

Zhengzhou Minzhong Pharmaceutical Co.,ltd

Contact:0086-371-65797115

Address:15/F,Jiangshan Bldg, NO.126 Huanghe Road,Zhengzhou, China
Anhui Asahikasei Chemical Co., Ltd

Contact:86-551-4259770

Address:No. 88 Linquan Road Hefei Anhui China
Weifang Dongxing Chitosan Factory

website:http://dxchitosan.lookchem.com/

Contact:13475651157

Address:Weifang city ,shandong province
SHIJIAZHUANG HENRYTE CHEMICALS CO,.LTD(expird)

Contact:+86-311-85208698 311-80837698

Address:NO.166, yuhua west road, SHIJIAZHUANG, China
NINGBO YINZHOU PRECISE COLOR CO.,LTD.

Contact:86-574-88139809 86-574-83033159

Address:Qiming Road,Yinzhou,Ningbo,China

Relevant to this article

Evidence for C(1)-N(2) bond scission in the isomerization of cis-1,3-disubstituted N_b-benzyl-1,2,3,4-tetrahydro-β-carbolines into their trans diastereomers under acidic conditions

Doi:10.1039/CC9960002477
(1996)
Preparation of 1,3-dienyl organotrifluoroborates and their Diels-Alder/cross-coupling reactions

Doi:10.1016/j.tet.2007.08.063
(2007)
Intercalation and Photochemical Behavior of Azobenzene Derivatives with Layered Polymer Crystals as the Organic Host

Doi:10.1246/cl.2003.712
(2003)
Stereoselective synthesis of highly functionalized cyclopropanes. Application to the asymmetric synthesis of (1S,2S)-2,3-methanoamino acids

Doi:10.1021/jo982528g
(1999)
First characterization of a compound with a tin-germanium double bond: The dimesityl(diisitylstanna)germene (Is)₂Sn=Ge(MeS)₂

Doi:10.1039/CC9960002621
(1996)
Organoalane-mediated isomerization of ascorbic and isoascorbic acid derivatives

Doi:10.1016/0957-4166(96)00427-2
(1996)

Article Doi