Evidence for C(1)-N(2) bond scission in the isomerization of cis-1,3-disubstituted Nb-benzyl-1,2,3,4-tetrahydro-β-carbolines into their trans diastereomers under acidic conditions

DOI: 10.1039/CC9960002477

Source and publish data:

Chemical Communications p. 2477 - 2478 (1996)

Update date:2022-08-02

Topics:

Authors:

Cox, Eric D.

Li, Jin Li, Jin

Hamaker, Linda K.

Yu, Peng

Cook Cook

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Article abstract of DOI:10.1039/CC9960002477

When cis diastereomer 13a was stirred in CF₃CO₂D the trans isomer 13b was isolated in 90% yield, while treatment of 13a with CF₃CO₂H-NaBH₄ provided a mixture of the C(1)-N(2) cleaved product 14 and th

Full text of DOI:10.1039/CC9960002477

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