Evidence for C(1)-N(2) bond scission in the isomerization of cis-1,3-disubstituted Nb-benzyl-1,2,3,4-tetrahydro-β-carbolines into their trans diastereomers under acidic conditions

DOI: 10.1039/CC9960002477

Source and publish data:

Chemical Communications p. 2477 - 2478 (1996)

Update date:2022-08-02

Topics:

Authors:

Cox, Eric D.

Li, Jin Li, Jin

Hamaker, Linda K.

Yu, Peng

Cook Cook

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1039/CC9960002477

When cis diastereomer 13a was stirred in CF₃CO₂D the trans isomer 13b was isolated in 90% yield, while treatment of 13a with CF₃CO₂H-NaBH₄ provided a mixture of the C(1)-N(2) cleaved product 14 and th

Full text of DOI:10.1039/CC9960002477

View Article Online / Journal Homepage / Table of Contents for this issue

View Article Online

Products guided by the article

Product name:(1R,3R)-2-Benzyl-1-[1,3]dithian-2-ylmethyl-2,3,4,9-tetrahydro-1H-β-carboline-3-carboxylic acid methyl ester

Cas No:185419-04-9

R&D Labs maybe for 185419-04-9

Zhuhai Rundu Pharmaceutical co.,Ltd

Contact:+86-756-7630755

Address:No.6,North Airport Road,Sanzao Town,Jinwan District
Changsha Easchem Co.,Limited

website:http://www.easchem.com

Contact:+86-731-89722861 89722891

Address:2/F-4/Bld Colorful Palace, No.605 Changsha Ave, Yuhua Area Changsha Hunan China.
SPE Chemicals Co.,Ltd

Contact:

Address:ROOM 1715, No#345 Jin Xiang Road, Pudong District
Watson International Ltd

Contact:+44 (0)2036089360-31

Address:Chanceryhouse,Chancery Lan
wuxi leji biology technology co., LTD

website:http://www.lejibio.com/

Contact:18362718864

Address:The Nanyue Road No. 2, Yixing City, Jiangsu Province

Relevant to this article

SYNTHESE DE POLYSILOXANES FLUORES. PARTIE 6. OLIGOMERES DE POLYMETHYL SILOXANES A EXTREMITES FLUOREES PAR CONDENSATION DE CHLOROSILANES FLUORES AVEC DES α,ο-DISILANOLS

Doi:10.1016/S0022-1139(00)82737-2
(1988)
Candida Rugosa lipase: Enantioselectivity enhancements in organic solvents

Doi:10.1016/0040-4039(96)01430-X
(1996)
Synthesis, antiproliferative and antiviral activity of imidazo[4,5- d]isothiazole nucleosides as 5:5 fused analogs of nebularine and 6- methylpurine ribonucleoside

Doi:10.1021/jm960605z
(1997)
Synthesis of Cyclohexanones through a Catalytic Cationic Cyclization of Alkynols or Enynes

Doi:10.1021/acs.orglett.8b00437
(2018)
A Facile Synthesis of Fluorochlorobromoacetic Acid

Doi:10.1007/BF00810292
(1990)
Synthesis and antibacterial activity of novel 7-(3-substituted-3 or 4- trifluoromethyl-1-pyrrolidinyl)-8-methoxyfluoroquinolones

Doi:10.1016/S0960-894X(98)00514-9
(1998)

Article Doi