European Journal of Medicinal Chemistry p. 915 - 918 (1996)
Update date:2022-09-26
Topics:
Conti, R. De
Gimenez, S. M. N.
Haun, M.
Pilli, R. A.
Castro, S. L. De
Duran, N.
The synthesis of several 3-(4'-bromo<1,1'-biphenyl>-4-yl)-3-(4-X-phenyl)-N,N-dimethyl-2-propen-1-amine derivatives is described.These compounds are potential trypanocide agents with relative low acute toxicities. the inhibition of growth of Escherichia coli by these drugs with different para-substitution on the phenyl moiety and their trypanocidal activities against epimastigote from Trypanosoma cruzi were investigated. - Keywords: Chagas's disease; trypanocide; Trypanosoma cruzi; aminopropene.
View MoreContact:0792-8228321
Address:10TH Floor No.121 binjiang Road Xunyang District
Shandong Dayi Chemical Co., Ltd.
website:http://www.dayi.com.cn
Contact:+86- 535-7388728. 15306386031
Address:No 1 Danya west road, Laiyang City, Shandong province
website:http://www.chinabarton.com
Contact:+86-573-82719618
Address:No. 162 Fumin Road, Honghe Town,
Yangzhou Zhongbao Pharmaceutical Co.,Ltd
Contact:+86-514-88290838
Address:Jiangsu Baoying county economic develpment zone in baoying avenue91
Shandong Xinke Petrochemical Co., Ltd.
Contact:+86-546-7277016
Address:Gudao Industrial Park, Hekou District, Dongying, Shandong Province, China
Doi:10.1021/acs.joc.7b01525
(2017)Doi:10.1016/S0040-4039(97)00148-2
(1997)Doi:10.1021/ja9637412
(1997)Doi:10.1021/tx9602067
(1997)Doi:10.1016/S0957-4166(00)00350-5
(2000)Doi:10.1021/jo962343e
(1997)
