European Journal of Medicinal Chemistry p. 915 - 918 (1996)
Update date:2022-09-26
Topics:
Conti, R. De
Gimenez, S. M. N.
Haun, M.
Pilli, R. A.
Castro, S. L. De
Duran, N.
The synthesis of several 3-(4'-bromo<1,1'-biphenyl>-4-yl)-3-(4-X-phenyl)-N,N-dimethyl-2-propen-1-amine derivatives is described.These compounds are potential trypanocide agents with relative low acute toxicities. the inhibition of growth of Escherichia coli by these drugs with different para-substitution on the phenyl moiety and their trypanocidal activities against epimastigote from Trypanosoma cruzi were investigated. - Keywords: Chagas's disease; trypanocide; Trypanosoma cruzi; aminopropene.
View Morewebsite:http://www.acrospharmatech.com
Contact:+1-3234804688
Address:Flat/RM 1502,Easey Commercial building 253-261 Hennessy Road,Wanchai，HongKong
Contact:13813902930 025-52714267
Address:20 Fengji Road, Yuhua Economic Development Zone, Nanjing, Jiangsu, P. R. China
Contact:+86-574-87065746
Address:10th Floor, No.787 Baizhang East Road,
Hangzhou Yingshanhua Pigment Chemicals Co.,Ltd.
Contact:+86-0150-58101658
Address:Nanyang Economic DevelopmentZong,Xiaoshan,Hangzhou,China
website:http://www.antaibio.com
Contact:0086-21-65663057
Address:Room 2108, Building 2，No. 489 Zhengli Road，200433
Doi:10.1021/acs.joc.7b01525
(2017)Doi:10.1016/S0040-4039(97)00148-2
(1997)Doi:10.1021/ja9637412
(1997)Doi:10.1021/tx9602067
(1997)Doi:10.1016/S0957-4166(00)00350-5
(2000)Doi:10.1021/jo962343e
(1997)
