European Journal of Medicinal Chemistry p. 915 - 918 (1996)
Update date:2022-09-26
Topics:
Conti, R. De
Gimenez, S. M. N.
Haun, M.
Pilli, R. A.
Castro, S. L. De
Duran, N.
The synthesis of several 3-(4'-bromo<1,1'-biphenyl>-4-yl)-3-(4-X-phenyl)-N,N-dimethyl-2-propen-1-amine derivatives is described.These compounds are potential trypanocide agents with relative low acute toxicities. the inhibition of growth of Escherichia coli by these drugs with different para-substitution on the phenyl moiety and their trypanocidal activities against epimastigote from Trypanosoma cruzi were investigated. - Keywords: Chagas's disease; trypanocide; Trypanosoma cruzi; aminopropene.
View MoreContact:410-273-7300; 800-221-3953
Address:4609 Richlynn Dr., PO Box 369, Belcamp, MD, 21017-0369, USA
Changzhou naidechemical Co.Ltd
Contact:+86-519-82589807
Address:NO.25,Houyang street,Jintan,Changzhou City
website:http://www.sagechem.com
Contact:+86-571-86818502
Address:Room C1301, New Youth Plaza, 8 Jia Shan Road, Hangzhou, China
SHOUGUANG BOYU CHEMICAL CO.,LTD
Contact:+86-536-8256719
Address:ROOM 1101&1103,BUILDING D,ZHONGTU MANSION,NO.6565 EAST FUSHOU STREET,WEIFANG CITY,SHANDONG,CHINA.
Changzhou Kingyo Chemical Corporation Ltd.
website:http://www.kingyochem.com
Contact:+86-519-85105717
Address:19# Wuqing North Road, Changzhou , Jiangsu, China
Doi:10.1021/acs.joc.7b01525
(2017)Doi:10.1016/S0040-4039(97)00148-2
(1997)Doi:10.1021/ja9637412
(1997)Doi:10.1021/tx9602067
(1997)Doi:10.1016/S0957-4166(00)00350-5
(2000)Doi:10.1021/jo962343e
(1997)
