Concise synthesis of taxol A-ring components: Remote diastereoselective additions of alkenyl lithiums to aldehydes

Article abstract of DOI:10.1016/S0040-4039(96)02159-4

The acid chloride 6 provides access to 7 (R,S and S,S) which upon bromine-lithium exchange undergoes remarkably highly diastereoselective additions to aldehydes; 7 is also readily elaborated into the acetal 10.