Tetrahedron Letters p. 9179 - 9182 (1996)
Update date:2022-07-29
Topics:
Mulzer, Johann
Mantoulidis, Andreas
The C(1)-C(9) segment 3 of the macrolides epothilon A and B 1, two new cytotoxic natural products, has been synthesized in a direct manner. Key steps in the synthesis are a stereoselective aldol reaction of 6 and 7 and a Brown allylation of 9.
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(1971)
