
Tetrahedron Letters p. 9353 - 9356 (1996)
Update date:2022-07-29
Topics:
Molina, Pedro
Fresneda, Pilar M.
Garcia-Zafra, Sagrario
New syntheses of the alkaloids eudistomin T and S are described. The key step, formation of the 1-phenylacetyl β-carboline, involves a tandem aza Wittig/electrocyclic ring closure process. The first synthesis of the alkaloid xestomanzamine A is achieved by coupling of a N-protected harmane, now available via aza Wittig/electrocyclic ring closure process, with a 5-lithioimidazole derivative.
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