Bioorganic and Medicinal Chemistry Letters p. 25 - 30 (1997)
Update date:2022-08-04
Topics:
Calligaro, David O.
Fairhurst, John
Hotten, Terrence M.
Moore, Nicholas A.
Tupper, David E.
4'-N-desmethyl olanzapine (2), olanzapine 4'-N-oxide (3) and 2-hydroxymethyl olanzapine (5), have been prepared and their pharmacology compared to that of the parent compound olanzapine (1). The 4'-N-quaternary glucuronide (8) has also been prepared.
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