An efficient synthesis of 6-substituted aminohexahydro-1H-1,4-diazepines from 2-substituted aminopropenals

DOI: 10.1248/cpb.44.2205

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 2205 - 2212 (1996)

Update date:2022-08-02

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Authors:

Harada, Hiroshi

Morie, Toshiya

Hirokawa, Yoshimi

Kato, Shiro

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Article abstract of DOI:10.1248/cpb.44.2205

Swern oxidation of 2-substituted amino-1,3-propanediols 20a - d, 38, 41, and 42 smoothly proceeded to give the oxidative dehydration products, 2-substituted aminopropenals 17a - d, 43, 45 and 46, respectively. Reaction of the intriguing 2-substituted amin

Full text of DOI:10.1248/cpb.44.2205

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