1,3-Asymmetric induction in enolate alkylation reactions of N-protected γ-amino acid derivatives

DOI: 10.1016/S0040-4039(96)02263-0

Source and publish data:

Tetrahedron Letters p. 163 - 166 (1997)

Update date:2022-09-26

Topics:

Authors:

Hanessian, Stephen

Schaum, Robert

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(96)02263-0

Dianions derived from N-TFA and N-Boc γ-amino acid esters and amides undergo highly stereoselective α-alkylation reactions. The roles of HMPA, of the cation, the electrophile, and of steric factors were studied.

Full text of DOI:10.1016/S0040-4039(96)02263-0

Products guided by the article

Product name:(R)-5-Phenyl-4-(2,2,2-trifluoro-acetylamino)-pentanoic acid methyl ester

Cas No:186903-53-7

R&D Labs maybe for 186903-53-7

Lanzhou huibang biological chemical technology Co., LTD

Contact:0931-7843964

Address:NO.2011,Yannan Road,Chengguan,
ZHEJIANG PAULA INDUSTRY CO.,LTD

website:http://www.haiqiangchem.com

Contact:86-571-86960380

Address:6th floor, building 2, dongfangmao business center, Xiacheng District, Hangzhou City, Zhejiang Province
Hangzhou Eastbiopharm Co.,Ltd.

Contact:+86-571-88931780

Address:Hangzhou,China
henan victory industry co.ltd

Contact:86-371-63655023

Address:No.85,jinshui road,zhengzhou,China
Ji'nan Orgachem Pharmaceutical Co.,Ltd

Contact:+86-531-82687810

Address:Jinan

Relevant to this article

Synthesis and pharmacology of conformationally restricted raloxifene analogues: Highly potent selective estrogen receptor modulators

Doi:10.1021/jm970688z
(1998)
Piperazine additions to C₆₀ - A facile approach to fullerene substitution

Doi:10.1039/b413173h
(2005)
Chiral 1,3-cyclobutane amino acids: Syntheses and extended conformations

Doi:10.1016/S0040-4039(97)00200-1
(1997)
Highly efficient synthesis and imaging studies of an arylpiperazine derivative as a 5-HT_1A receptor imaging agent

Doi:10.1246/cl.2006.1304
(2006)
Organocatalyzed synthesis and biological activity evaluation of hybrid compounds 4H-pyrano[2,3-b]pyridine derivatives

Doi:10.1080/00397911.2020.1757717
(2020)
Synthesis of sulfo and sialyl Lewis(x) analogs with a mannose at the reducing end

Doi:10.1016/S0960-894X(97)00181-9
(1997)

Article Doi