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Synthesis of sulfo and sialyl Lewis(x) analogs with a mannose at the reducing end

DOI: 10.1016/S0960-894X(97)00181-9

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 1157 - 1160 (1997)

Update date:2022-09-26

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Authors:

Huang, Bao-GuoHuang, Bao-Guo

Locke, Robert D.Locke, Robert D.

Jain, Rakesh K.Jain, Rakesh K.

Matta, Khushi L.Matta, Khushi L.

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Article abstract of DOI:10.1016/S0960-894X(97)00181-9

Stereoselective syntheses of 3-O-sulfo and 3-O-sialyl Lewis(x) analogs 1 and 2 were accomplished. Compound 1 showed greater inhibitory activity than the natural ligand sialyl Lewis(x) against P and L-selectin.

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Full text of DOI:10.1016/S0960-894X(97)00181-9

Products guided by the article

Product name:2,2-Dimethyl-propionic acid (2R,3S,4S,5R,6S)-3,4,5-triacetoxy-6-[(2R,3S,4R,5R,6S)-2-benzyloxymethyl-5-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-4-hydroxy-6-phenylsulfanyl-tetrahydro-pyran-3-yloxy]-tetrahydro-pyran-2-ylmethyl ester

Cas No:191331-64-3

191331-64-3

R&D Labs maybe for 191331-64-3

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