Synthesis of sulfo and sialyl Lewis(x) analogs with a mannose at the reducing end

DOI: 10.1016/S0960-894X(97)00181-9

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 1157 - 1160 (1997)

Update date:2022-09-26

Topics:

Authors:

Huang, Bao-Guo

Locke, Robert D.

Jain, Rakesh K.

Matta, Khushi L.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0960-894X(97)00181-9

Stereoselective syntheses of 3-O-sulfo and 3-O-sialyl Lewis(x) analogs 1 and 2 were accomplished. Compound 1 showed greater inhibitory activity than the natural ligand sialyl Lewis(x) against P and L-selectin.

Full text of DOI:10.1016/S0960-894X(97)00181-9

Products guided by the article

Product name:2,2-Dimethyl-propionic acid (2R,3S,4S,5R,6S)-3,4,5-triacetoxy-6-[(2R,3S,4R,5R,6S)-2-benzyloxymethyl-5-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-4-hydroxy-6-phenylsulfanyl-tetrahydro-pyran-3-yloxy]-tetrahydro-pyran-2-ylmethyl ester

Cas No:191331-64-3

R&D Labs maybe for 191331-64-3

Jiangsu King Road New Materials Co., Ltd.

website:http://www.jskingroad.com

Contact:0519-85720726 0519-85720721 13584535752

Address:No.1,Weihua Road,Xinbei District,Changzhou City,Jiangsu Province
Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

website:http://www.jlpharms.com

Contact:86-571-86982636

Address:Rm A606, Fuyi Center, jianqiao street
Shijiazhuang Haitian Amino Acid Co., Ltd.

Contact:+86-311-88908111

Address:Shijiazhuang Hebei province,China
Guangxi Shanyun Biochemical Science and Technology Co., Ltd

Contact:+86-0772--6828887

Address:#2 Industrial Park of Luzhai County, Liuzhou, Guangxi, China
Zibo Linzi Darong Fine Chemical Co., Ltd(expird)

Contact:86-532-67773200; 15689126900

Address:Qidu town,Linzi district,Zibo city,Shandong province,China

Relevant to this article

83. Chiral 2-Aryl-2-methyl-2H-1-benzopyrans: Synthesis, Characterization of Enantiomers, and Barriers to Thermal Racemization

Doi:10.1002/hlca.19970800409
(1997)
Stereoselective synthesis of the C-analogue of β-D-glucopyranosyl serine

Doi:10.1039/a703063k
(1997)
Doi:10.1080/01615440209604133
(1939)
Doi:10.1039/j39680001874
(1968)
Doi:10.1246/bcsj.41.635
(1968)
Rhodium-catalyzed silylformylation of acetylenic bonds: Its scope and mechanistic considerations

Doi:10.1021/om970549f
(1997)

Article Doi