An enantioconvergent route to(-)-kainic acid

Article abstract of DOI:10.1016/S0040-4039(96)02467-7

A new stereocontrolled route to (-)-kainic acid, the representative of the kainoid amino acids and exhibiting insecticidal, anthelmintic and neuroexcitatory properties, has been devised in an enantioconvergent way using either (+)- or (-)-ketodicyclopentadiene as the starting material by employing a concurrent retro-Diels-Alder reaction and intramolecular ene reaction as the key step.