Tetrahedron p. 1777 - 1786 (1997)
Update date:2022-08-03
Topics:
veras, Anniken T.
Gundersen, Lise-Lotte
Rise, Frode
6-Vinylpurines readily undergo Diels-Alder reactions with dienes. Both reactivity and endo selectivity are greatly improved when the cycloadditions are performed in the presence of zinc chloride. Lewis acid mediated Diels-Alder reaction of 6-vinylpurine riboside was employed as a key step in the synthesis of a nucleoside with structural resemblance to potent A1 adenosine agonists.
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(1997)Doi:10.1016/S0040-4039(97)01174-X
(1997)
