Lipid A and related compounds. XXXII. Synthesis of biologically active N-acylated L-homoserine-containing D-glucosamine-4-phosphate derivatives structurally related to lipid A

DOI: 10.1248/cpb.45.312

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 312 - 320 (1997)

Update date:2022-07-30

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Authors:

Miyajima, Keisuke

Achiwa, Kazuo

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Article abstract of DOI:10.1248/cpb.45.312

New N-acylated L-homoserine-containing non-phosphorylated and phosphorylated D-glucosamine derivatives were synthesized as mimicks of lipid A disaccharide. Some of the synthesized compounds exhibited mitogenic activity and nitric oxide (NO) productivity.

Full text of DOI:10.1248/cpb.45.312

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