Bioorganic and Medicinal Chemistry Letters p. 1311 - 1316 (1997)
Update date:2022-07-30
Topics:
Toepfer, Alexander
Kretzschmar, Gerhard
Four piperidine carboxylic acid derivatives designed as mimetics of the sialyl Lewis X determinant were synthesized. Their inhibitory potency for selectin mediated cell adhesion was evaluated in cell culture assays, in vivo and in a reperfusion model. Compound 7 showed strong inhibition of leukocyte adhesion in rats and a powerful decrease of the incidence of arrhythmias in a reperfusion model in isolated rabbit hearts.
View MoreContact:(1) 206-3550089
Address:5115 NE 8TH PL, Renton, WA 98059 USA
Shanghai Micro-mega Industry Co., Ltd.
Contact:0086-21-34628682;57153848
Address:Rm413,No.413,West Meilong Road, Minhang District,Shanghai P R China
Tianjin Tensing Fine Chemical Research Develop Centre
Contact:86-022-23718576,13032267585
Address:2-2-201,13 Guiyuan road,Huayuan Industry district,Tianjin,china
LIAOYANG WANRONG CHEMICALS COMPANY LIMITED
Contact:86-419-2390789
Address:XINLI VILLAGE , DONG NINGWEI COUNTY,TAIZIHE DISTRICT, LIAOYANG , LIAONING
ZHANGJIAGANG FREE TRADE ZONE YONG HAN INTERNATIONAL TRADING CO., LTD(expird)
Contact:86 512 57910558
Address:qianjin M road
Doi:10.1021/ic970073s
(1997)Doi:10.1021/jo970284e
(1997)Doi:10.1021/om970059n
(1997)Doi:10.1021/ja01233a501
(1944)Doi:10.1016/S0957-4166(97)00060-8
(1997)Doi:10.1021/jo972035w
(1998)
