Bioorganic and medicinal chemistry letters p. 425 - 428 (1997)
Update date:2022-08-05
Topics:
Groetli, Morten
Douglas, Mark
Beijer, Barbro
Eritja, Ramon
Stroat, Brian
A new synthetic route has been devised for the preparation of 2'-O-alkyl guanosine derivatives. Utilizing a strategy of minimal protection, the alkylation was performed on partly protected guanosine using an alkyl halide and a sterically hindered strong organic base.
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Doi:10.1016/S0040-4039(00)74423-6
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(1978)
