
Journal of Heterocyclic Chemistry p. 145 - 151 (1997)
Update date:2022-08-03
Topics:
Chan
Hong
Kuyper
Jones
Baccanari
Tansik
Boytos
Rudolph
Brown
A series of novel 1,3-diamino-7,8,9,10-tetrahydropyrido[3,2-f]quinazolines were synthesized starting from 6-amino-5-cyanoquinoline (4). These compounds inhibited Candida albicans dihydrofolate reductase with K(i) values of ≤ 0.60 nM. One analogue exhibite
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Doi:10.1021/om960971g
(1997)Doi:10.1021/ja01041a016
(1969)Doi:10.1039/c3ra45576a
(2013)Doi:10.1016/S0968-0896(96)00200-3
(1997)Doi:10.1016/S0040-4039(97)00412-7
(1997)Doi:10.1055/s-1997-778
(1997)