Design of peptidomimetic ligands for the pp60(src) SH2 domain

DOI: 10.1016/S0968-0896(96)00200-3

Source and publish data:

Bioorganic and Medicinal Chemistry p. 41 - 47 (1997)

Update date:2022-08-03

Topics:

Authors:

Plummer, Mark S.

Lunney, Elizabeth A.

Para, Kimberly S.

Shahripour, Aurash

Stankovic, Charles J.

Humblet, Christine

Fergus, James H.

Marks, James S.

Herrera, Roman

Hubbell, Susan

Saltiel, Alan

Sawyer, Tomi K.

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Article abstract of DOI:10.1016/S0968-0896(96)00200-3

Potent ligands of the Src SH2 domain, discovered through structure-based drug design efforts, with the general structure Ac-pTyr-Glu-NRR' are disclosed.

Full text of DOI:10.1016/S0968-0896(96)00200-3

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Product name:Pentanoic acid, 5-[[3-[3-(2-amino-2-oxoethoxy)phenyl]propyl]amino]-4-[[(9H-fluoren-9-yl methoxy)carbonyl]amino]-5-oxo-, 1,1-dimethylethyl ester, (S)-

Cas No:189393-47-3

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