Formation of cyclopropyl carbinols through a highly diastereoselective hydrozirconation of vinyloxirane derivatives

Article abstract of DOI:10.1016/S0040-4039(97)00233-5

Cyclopropyl carbinol derivatives were efficiently prepared through a highly diastereoseletive hydrozirconation of vinyloxiranes and the intramolecular attack of the generated alkylzirconocene with the inversion of the configuration at the reacting oxirane carbon.