(S)-Ethyl 4,4-dimethyl pyroglutamate as a new 'quat' chiral auxiliary in aldol condensations

DOI: 10.1016/S0957-4166(97)00028-1

Source and publish data:

Tetrahedron Asymmetry p. 669 - 671 (1997)

Update date:2022-08-03

Topics:

Authors:

Ezquerra, Jesus

Rubio, Almudena

Martin, Justina

Navio, Jose Luis Garcia

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0957-4166(97)00028-1

Enolates I, derived from the N-propionyl derivative of the 'quat' chiral auxiliary (S)-ethyl 4,4-dimethyl pyroglutamate 4 undergo highly stereoselective aldol reactions, which upon hydrolysis and removal of the chiral auxiliary yields the (2R,3R)-3-hydrox

Full text of DOI:10.1016/S0957-4166(97)00028-1

Products guided by the article

Product name:(2S)ethyl N-[2R,3R-(3-hydroxy-2-methyl-3-phenylpropionyl)]-4,4-dimethylpyroglutamate

Cas No:189098-09-7

R&D Labs maybe for 189098-09-7

Jiangsu Jiuri Chemical Co.,Ltd.

Contact:+86-519-82118868

Address:Tianwang Town, Jurong City, Jiangsu Province, China
Zhaodu Fine Chemical Plant

Contact:86-310-8067016

Address:East Fuhua Road,Tiexi Chemical Industrial Estate,Hebei,China
Jinan Hongfangde Pharmatech Co.,Ltd

Contact:86-531-88870908

Address:F Bldg. West Unit North Area of Univ. Tech. Garden Xinyu Rd. Jinan New & High Tech Industry Development Zone Shandong, China
ZiBO KuoDing Trade company Ltd

website:http://www.sdzbkd.com

Contact:86-13361591822

Address:GongQingTuan road
WUHU HUAHAI BIOLOGY ENGINEERING CO LTD

Contact:+86-553-3836920

Address:7/F NO.82 LAODONG ROAD WUHU CHINA

Relevant to this article

Synthetic studies of antitumor macrolide laulimalide: Enantioselective synthesis of the C₃-C₁₄ segment by a catalytic hetero Diels-Alder strategy

Doi:10.1016/S0040-4039(97)00416-4
(1997)
A straightforward route to hydantocidin analogues with pyranose ring structure

Doi:10.1016/S0040-4020(97)00213-5
(1997)
Doi:10.1039/j39670002268
(1967)
A more sustainable isothiocyanate synthesis by amine catalyzed sulfurization of isocyanides with elemental sulfur

Doi:10.1039/d0ra10436a
(2021)
Doi:10.1007/BF00476780
()
Regioselective synthesis of 1,5-diaryl-1H-imidazoles by palladium-catalyzed direct arylation of 1-aryl-1H-imidazoles

Doi:10.1021/jo050274a
(2005)

Article Doi