New organohypervalent iodine reagents for α-methylphosphonylations and α-diphenyl- and α-dimethylphosphinylations

Article abstract of DOI:10.1016/S0040-4039(97)00388-2

[Hydroxy(((phenoxy)(methyl)phosphoryl)oxy)iodo]benzene (1), [hydroxy(((diphenyl)phosphoryl)oxy)iodo]benzene (2) and [hydroxy(((dimethyl)phosphoryl)oxy)iodo]benzene (3), obtained from the reaction of iodosobenzene with phenyl methylphosphonic acid, diphenyl- and dimethylphosphinic acid, respectively, effect the introduction of the corresponding phosphonate or phosphinate groups α- to ketone and eater carbonyl groups. Phenylacetylene is transformed by reagents 1-3 into the corresponding α-functionalized acetophenone derivatives.