No-carrier-added asymmetric synthesis of α-methyl-α-amino acids labelled with fluorine-18

DOI: 10.1016/S0040-4020(97)00265-2

Source and publish data:

Tetrahedron p. 5785 - 5796 (1997)

Update date:2022-08-03

Topics:

Authors:

Damhaut, Philippe

Lemaire, Christian

Plenevaux, Alain

Brihaye, Claude

Christiaens, Leon

Comar, Dominique

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Article abstract of DOI:10.1016/S0040-4020(97)00265-2

Various [¹⁸F]fluoro aromatic α-methyl-L-amino acids T1 have been synthesized with high enantiomeric purity (ee > 97%). These new radiopharmaceuticals for Positron Emission Tomography (PET), potential inhibitors of enzymatic functions, were regi

Full text of DOI:10.1016/S0040-4020(97)00265-2

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